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August 13, 2024 in Genitourinary (GU)

GU013

The Phase III ‘High Five Trial’ Five Fraction Radiation For High-Risk Prostate Cancer
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May 20, 2024 in Genitourinary (GU)

MK5684

A Phase 3 Randomized, Open-label Study of MK-5684 Versus Alternative Abiraterone Acetate or Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) Previously Treated With Next-generation Hormonal Agent (NHA) and…
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May 14, 2024 in Genitourinary (GU)

EA8211

A Phase III Trial of Stereotactic ablative radiotherapy for Oligometastatic Advanced Renal Carcinoma (SOAR)
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April 30, 2024 in Genitourinary (GU)

A032103

MODERN: An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of Adjuvant Therapy in Urothelial Cancer
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October 18, 2023 in Genitourinary (GU)

SGNDV-001/KN-D74

An Open-label, Randomized, Controlled Phase 3 Study of Disitamab Vedotin in Combination with Pembrolizumab Versus Chemotherapy in Subjects with Previously Untreated Locally Advanced or Metastatic Urothelial Carcinoma that Expresses HER2…
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December 14, 2022 in Genitourinary (GU)

S2200

A Phase II Randomized Trial of Cabozantinib With or Without Atezolizumab in Patients with Advanced Papillary Renal Cell Carcinoma (PAPMET2)
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October 11, 2022 in Genitourinary (GU)

GU012

Randomized Phase II Stereotactic Ablative Radiation Therapy (SABR) For Metastatic Unresected Renal Cell Carcinoma (RCC) Receiving Immunotherapy (SAMURAI) (NCT# 05327686)
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September 21, 2022 in Genitourinary (GU)

A032101

A phase 2 trial of ADT interruption in patients responding exceptionally to AR pathway inhibitor in metastatic hormone-sensitive prostate cancer (MHSPC): A-DREAM NCT #05241860
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August 26, 2022 in Genitourinary (GU)

EA8191

EA8191: Phase III Study of Local or Systemic Therapy INtensification DIrected in Prostate CAncer Patients with Post-ProstaTEctomy Biochemical Recurrence (INDICATE) (NCT04423211)
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July 11, 2022 in Genitourinary (GU)

S1937

S1937: A Phase III Randomized Trial of Eribulin (NSC #707389) with or without Gemcitabine versus Standard of Care (Physician’s Choice) for Treatment of Metastatic Urothelial Carcinoma Refractory to, or Ineligible…
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July 11, 2022 in Genitourinary (GU)

S1931

S1931: PHASE III TRIAL OF IMMUNOTHERAPY-BASED DRUG COMBINATION THERAPY WITH OR WITHOUT CYTOREDUCTIVE NEPHRECTOMY FOR METASTATIC RENAL CELL CARCINOMA (PROBE TRIAL) (Study SWOG 1931) (NCT#0451059)
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July 11, 2022 in Genitourinary (GU)

S1806

S1806: Phase III Randomized Trial of Concurrent Chemoradiotherapy with or without Atezolizumab in Localized Muscle Invasive Bladder Cancer
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July 11, 2022 in Genitourinary (GU)

S1802

Phase III Randomized Trial of Standard Systemic Therapy (SST) versus Standard Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor in Metastatic Prostate Cancer).
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June 30, 2022 in Genitourinary (GU)

GU011

GU011: A Phase II Double-Blinded, Placebo Controlled Trial of Prostate Oligometastatic Radiotherapy with or without Androgen Deprivation Therapy in Oligometastatic Prostate Cancer (NRG PROMETHEAN) (NCT# 05053152)
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June 30, 2022 in Genitourinary (GU)

GU010

GU010: Parallel Phase III Randomized Trials of Genomic Risk Stratified Unfavorable Intermediate Risk Prostate Cancer: De-Intensification and Intensification Clinical Trial Evaluation (GUIDANCE) (NCT#05050084)
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June 30, 2022 in Genitourinary (GU)

GU009

GU009: Parallel Phase III Randomized Trials For High Risk Prostate Cancer Evaluating De-Intensification For Lower Genomic Risk and Intensification of Concurrent Therapy for Higher Genomic Risk with Radiation (Predict-RT*) (NCT#04513717)…
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June 30, 2022 in Genitourinary (GU)

GU008

GU008: Randomized Phase III Trial Incorporating Abiraterone Acetate with Prednisone and Apalutamide and Advanced Imaging into Salvage Treatment for Patients with Node-Positive Prostate Cancer after Radical Prostatectomy (NCT #04134260)
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June 30, 2022 in Genitourinary (GU)

EA8192

EA8192: A Phase II/III Trial of MEDI4736 (Durvalumab) and Chemotherapy for Patients with High Grade Upper Tract Urothelial Cancer Prior to Nephroureterectomy
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June 30, 2022 in Genitourinary (GU)

AREN1721

Axitinib and Nivolumab in Treating Participants With Unresectable or Metastatic TFE/Translocation Renal Cell Carcinoma
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June 30, 2022 in Genitourinary (GU)

A032001

A032001: Testing the addition of the anti-cancer drug, cabozantinib, to the usual immunotherapy treatment, avelumab, in patients with metastatic urothelial cancer
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June 30, 2022 in Genitourinary (GU)

A031801

A031801: A Phase II Randomized Trial of Radium-223 dichloride and Cabozantinib in Patients with Advanced Renal Cell Carcinoma with Bone Metastasis (RadiCaL)
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June 29, 2022 in Genitourinary (GU)

A031702

A031702: A phase II study of Ipilimumab, CabOzantinib, and NIvolumab in rare genitourinary Cancers (ICONIC) (NCT03866382)
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June 29, 2022 in Genitourinary (GU)

A031701

Gemcitabine Hydrochloride and Cisplatin in Treating Participants With Invasive Bladder Urothelial Cancer
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